Coffee and Women Health
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https://doi.org/10.5281/zenodo.11374924Keywords:
Coffee, Pregnancy, Women HealthAbstract
Kahve, dünyada en çok tüketilen kafein içeren içeceklerden biridir. Önemli miktarda klorojenik asit ve kafein dahil olmak üzere birçok farklı kimyasal bileşen içerir. Ayrıca birçok popülasyonda kahvenin ana kafein kaynağı olduğu da bilinmektedir. Kafeinin en sık tüketilen psikoaktif uyarıcı olduğu bilinmektedir ve özellikle A1 ve A2A adenozin reseptör antagonisti olarak biyolojik aktivite göstermektedir. Klorojenik asit, kafeik asit ve melanoidin de kahvede bulunan antioksidanlar olarak gösterilmektedir. Önemli etkileri olan polifenollerin trans-sinnamik ve kinik asit yapıları arasında yer aldığı gösterilmiştir. Glikoz ve yağ metabolizmasında rol oynarlar ve diyabet, kardiyovasküler hastalıklar, obezite ve kanserle ilişkilidirler. Kahve, karbonhidratlar, yağlar, nitrojen bileşikleri, vitamin ve mineraller, alkaloidler ve fenolik bileşikler gibi birçok besin açısından zengin bir içecek olarak tanımlanmaktadır. Geçmişte yapılan çalışmalar kahve tüketiminin sağlığa olumsuz etkisi olduğunu gösterse de artık bazı kronik hastalıklara karşı koruyucu olabilecek bileşenler içerdiği kabul ediliyor. Fiziksel performansı arttırdığı, obezite ve tip II diyabete karşı koruduğu, felç, karaciğer, prostat ve kolorektal kanser riskini %20 azalttığı, Parkinson riskini %25 azalttığı, beyin fonksiyonlarını iyileştirdiği ve hastalıklara karşı koruduğu bulunmuştur. demansla mücadelenin yanı sıra depresyonla mücadeleye destek oluyor ve intihar riskini %50 oranında azaltıyor. Kahve tüketenlerde ölüm oranının, tüketmeyenlere göre daha düşük olduğu gösterilmiş olup, özellikle kadınlarda kahve tüketimi arttıkça endometriyum ve meme kanseri ile kalp-damar hastalıkları riskinin azaldığının altı çizildi. Kahvenin kadınlar üzerindeki olası faydalı etkilerinin yanı sıra kısırlık, hamilelikte düşük yapma riski, emziren annelerde aşırı anksiyete gelişimi, uykusuzluk, yenidoğanda sinirlilik, kemik kırıklarında artış gibi risk faktörlerini gösteren çalışmalar bulunmaktadır. Bu derlemenin amacı kahve tüketiminin kadın sağlığına etkilerini araştıran çalışmaları incelemek ve yorumlamaktır.
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