The influence of patient demographics, stage of disease, and history of corticosteroid injections on the effectiveness of platelet-rich plasma in the treatment of knee osteoarthritis
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https://doi.org/10.5281/zenodo.11374191Keywords:
Osteoarthritis, PRP, InjectionAbstract
Osteoarthritis is the predominant form of non-inflammatory arthritis, and it frequently affects the knee joint. The basis of platelet-rich plasma (PRP) treatment is to obtain supraphysiological doses of growth factors by concentrating the platelets. Thus it is intended to accelerate wound healing and achieve better functional improvement (2, 3, 4). For knee osteoarthritis treatment, PRP is administered as repeated intraarticular injections.
Our study aimed to determine the impact of two PRP administrations, with an interval of four weeks, on pain, Cincinnati Knee Rating System and the Lysholm Knee Score evaluation in patients with knee osteoarthritis. In addition, we wanted to explore the relation of PRP treatment with the stage of osteoarthritis, obesity, age, gender, and intraarticular steroid administration within the last 6 months.
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