Comparison of Gem Premier 5000 Device and Radiometer ABL 800 Flex Blood Gas Analyzers

Abstract

Objective: In this study, we aimed to compare the analytical performance of the Gem Premier 5000 (Instrumentation Laboratory, Bedford, MA, USA) blood gas analyzer with the ABL 800 Flex (Radiometer, Copenhagen, Denmark) blood gas analyzer used in our laboratory.

Methods: 96 consecutive samples sent to Tokat Gaziosmanpaşa University Hospital Central Laboratory between 1-20 May 2023 were included in the study. Samples are taken into a 2 mL blood gas injector containing 70 IU of lithium heparin (Ayset Medical Products (Seyhan, Adana, Turkey) and analyzed with two devices consequetively. The parameters of pH, pCO2, pO2, ctHb, HCT, sO2, O2Hb, COHb, HHb, MetHb, Na, K+, Cl, Ca2+, Glucose, Lactate and HCO3 were evaluated. The significance test of the difference between the two spouses, Pearson correlation and Bland-Altman analysis were used. SPSS 19 (IBM SPSS Statistics 19, SPSS inc., An IBM Co., Somers, NY) was used.

Results:  In comparison of the two groups, clinically negligible, statistically significant difference was found between all parameters except pH, pO2, HCT, MetHb, Na, Cl and HCO3 (p<0.001). Pearson correlation coefficients (CCC) of the parameters were in the range of 0.721-0.999. Bland-Altman values for pH, pCO2, MetHb and lactate were Bias :0.013, SD :0.031721, IIa :-0.04951, uIa :0.07484, Bias -3.44286, SD : 3.378443, IIa:-10.0646, UIa : 3.178891, Bias : -0.1, SD : 0.676123, IIa: -1.4252, uIa : 1.225202, Bias : 0.269231, SD : 0.217503, IIa:-0.15708, ula: 0.695537 respectively.

Conclusion: The GEM PREMIER 5000 was correlated with the Radiometer ABL800 Flex in terms of results and was acceptable in clinical practice. GEM PREMIER 5000 has been deemed suitable for use at the bedside due to its advantages like ease of use and short maintenance time.