ACUTE SKIN REACTIONS IN BREAST CANCER PATIENTS RECEIVING RADIOTHERAPY
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https://doi.org/10.5281/zenodo.6976503%20Keywords:
Acute skin reaction, breast cancer, radiotherapyAbstract
Breast cancer is the most common type of cancer in women. One of the main treatment methods applied in breast cancer is radiotherapy. Acute skin reactions in the area where radiotherapy is applied adversely affect the patient's quality of life, the continuity of treatment, duration, and adherence to treatment. Skin reactions that start within 2-3 weeks after the start of treatment are often; It manifests itself as erythema, pain, itching, dry and wet desquamation. The most important step in the management of skin reactions is prevention initiatives. Although there is no standard practice for the prevention and treatment of skin reactions, but there are many studies on this subject. In the studies, many products such as steroid-containing creams, Calendula, Trolamine, Hyaluronic Acid, Olive oil, ready-made dressings, etc. were used.
References
Alço G., Dinçer M., Ece T. İğdem Ş., Okkan S. Meme kanseri radyoterapisi sonrası gelişen bronşiolitis obliterans organize -pnömoni (BOOP) sendromu. The Journal of Breast Health. 2009; 5(3): 157-161.
Andrade M., Clapis MJ., Nascimento TG., Gozzo TO., Almeida AM. Prevention of skin reactions due to teletherapy in women with breast cancer: a comprehensive review. Rev. Latino-Am. Efermagem. 2012; 20(3):604-611.
Bensadoun RJ., Humbert P., Krutman J., Luger T., Triller R., Rougier A. et al. Daily baseline skin care in the prevention, treatment, and supportive care of skin toxicity in oncology patients: Recommendations from a multinational expert panel. Cancer Management and Research. 2013; 5: 401–408.
Bolderston A., Lloyd NS., Wong RKS., Holden L., Robb-Blenderman L. The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline. Support Care Cancer. 2006; 14: 802–817.
Chitapanarux İ., Tovanabutra N., Chiewchanvit S. Sripan P., Chumachote A., Nobnop W. et al. Emulsion of olive oil and calcium hydroxide for the prevention of radiation dermatitis in hypofractionation post-mastectomy radiotherapy: A randomized controlled trial. Breast Care. 2019; 14:394–400.
Cui Z, Xin M, Yin H, Zhang J, Han F. Topical use of olive oil preparation to prevent radiodermatitis: results of a prospective study in nasopharyngeal carcinoma patients. Int J Clin Exp Med. 2015; 8: 11000–11006.
Depboylu B. Meme kanserinde uygulanan radyoterapinin erken ve geç etkileri. Türkiye Klinikleri J Med Pathol-Special Topics 2016; 1(3):40-48.
Drost L., Li N., Vesprini D., Sangha A., Lee J., Leung E. et al. Prospective Study of Breast Radiation Dermatitis. Clinical Breast Cancer, 2018; 18(5): e789-e795.
Fuzissaki MA., Paiva CE., Gozzo TO., Maia MA., Lajolo Canto PP., Paiva Maia YC. Is there agreement between evaluators that used two scoring systems to measure acute radiation dermatitis? Medicine. 2019; 98(15): 1-7.
Genç M., Korcum AF., Yavuz MN. Meme kanserinde radyoterapi uygulamaları. Turkiye Klinikleri J Med Oncol-Special 60 Topics. 2012; 5(2):60-65.
Gündoğdu F. Radyoterapi Alan Meme Kanseri Kadınlarda İki Farklı Yöntemle Uygulanan Nefes Egzersizinin Yorgunluk ve Uyku Kalitesi Üzerine Etkisi: Randomize Kontrollü Çalışma [Doktora Tezi]. Ankara: Yıldırım Beyazıt Üniversitesi; 2019.
Hornsby C., Fletcher J., Blyth CM. The production of a best practice statement in the skincare of patients receiving radiotherapy. Journal of Radiotherapy in Practice. 2004; 4:126-130.
Karagöz G. Radyoterapiye Bağlı Cilt Reaksiyonlarında Hemşirelik Bakımı. Radyasyon Onkolojisinde Temel Yaklaşımlar, İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri Sempozyum Dizisi No: 79, Kasım 2012; İstanbul.
Kaya D. Radyoterapiye bağlı cilt reaksiyonları. Hemşireler İçin Kemoterapi Kursu. Ed. Kaya D., Kutlu L. İstanbul: Dilek Mat; 2013: 67-72.
Kirova YM., Fromantin I., De Rycke Y., Fourquet A., Morvan E., Padiglione S., et al. Can we decrease the skin reaction in breast cancer patients using hyaluronic acid during radiation therapy? Results of phase III randomized trial. Rad. Oncol. 2011; 100: 205-209.
Leonardi MC., Gariboldi S., Ivaldi GB., Ferrari A., Serafini F., Didier F. et al. A double-blind, randomized vehicle-controlled clinical study to evaluate the efficacy of MAS065D in limiting the effects of radiotion on the skin: interim analysis. Eur J Dermatol. 2008; 18(3):317-321.
Liguori V., Gulilemin C., Pesce GF., Mirimanoffb RO., Berniera J. Double-blind randomized clinical study comparing hyaluronic acid cream to placeba in patients treated with radiotherapy. Radiother Oncol. 1997; 42(2):155-161.
M. Fernández-Castro MF., Gil BM., García P., Vallecillo ML., Puig MEG. Effectiveness of semi-permeable dressings to treat radiation–induced skin reactions. A systematic review. Eur J Cancer Care. 2017; 26:1-8.
Mcquestıon M. Evıdence-Based skın care management in radiation therapy: clinical update. Seminars in Oncology Nursing. 2011; 27(2): e1-e17.
Noble-Adams R. Radiation induced skin reactions. Development of a measurement tool. BJN. 1999; 8(18): 1208-1211.
Ören K. Radyoterapi Cilt Reaksiyonları. Ed. Can G. Onkoloji Hemşireliği. 1. Baskı. İstanbul: Nobel Tıp Kitapevi; 2014: 455-466.
Ören K., Can G. Radyodermatit. Ed. Can G. Onkoloji Hemşireliği Genişletilmiş ve Güncellenmiş 2. Baskı. İstanbul: Nobel Tıp Kitapevi, 2020: 503-512.
Özsaran Z. Meme koruyucu cerrahi sonrası radyoterapi. Turkiye Klinikleri Radiat Oncol-Special Topics. 2017;3(3):171-7.
Öztürk E. Radyoterapi Alan Baş ve Boyun Kanserli Hastalarda Yaşam Kalitesi ve Yaşam Kalitesini Etkileyen Faktörler [Yüksek Lisans Tezi]. İstanbul: İstanbul Üniversitesi; 2011.
Pommier P., Gomez F., Sunyach MP., D’Hombres A., Carrie C., Montbarbon X. Phase III randomized trial fo Calendula officinalis compared with trolamine fort he prevention of acute dermatitis during irradiation for breast cancer. J Clin Oncol. 2004; 22:1447-1453.
Primavera G. Carrera M. Berardesca E. Pinnaro P., Messina M., Arcangeli G. A double-blind vehicle-controlled clinecal study to evaluate the eficacy of MAS066D (Xclair) a hyaluronik acid-based formulation, in the management of radiation-induced dermatitis. Cutan Ocul Toxicol. 2006; 25(3):165-171.
Robijns J., Lodewijckx J., Claes S., Bever LV., Pannekoeke L., Censabella S. et al. Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial). Radiotherapy and Oncology. 2021; 158: 268–275.
Schmeel LC., Koch D., Schmeel FC., Bücheler B., Leitzen C., Mahlmann B. et al. Hydrofilm polyurethane films reduce radiation dermatitis severity in hypofractionated whole-breast ırradiation: an objective, Intra-Patient Randomized Dual-Center Assessment. Polymers 2019; 11, 2112: 1-15.
Seité S., Bensadoun RJ., Mazer JM. Prevention and treatment of acute and chronic radiodermatitis. Breast Cancer - Targets and Therapy. 2017; 9: 551–557.
Seyhan Ak E, Çavdar İ. Meme kanserinde sistemik tedaviler (kemoterapi, hormonoterapi, hedefe yönelik tedavi) ve hemşirelik bakımı. Meme Kanseri ve Hemşirelik Bakımı. Türkiye Klinikleri. 2019; 1:20-27.
Sis Çelik A. Radyoterapi sonucu gelişen yan etkiler ve hemşirelik yaklaşımı. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2014; 3(3): 933-947.
Tekbaş S, Dal Yılmaz Ü. Meme kanserinde radyoterapi uygulanan hastanın hemşirelik bakımı. Meme Kanseri ve Hemşirelik Bakımı, Türkiye Klinikleri. 2019;1:28-34.
Temur K, Kapucu S. Meme Kanseri İlişkili Lenfödem Gelişimini Önlemede ve Yaşam Kalitesini Yükseltmede Etkin Yöntem Kendi Kendine Lenfödem Yönetimi. Osmangazi Journal of Medicine. 2018; 40(1):121-129.
Ünsal D., Aksu A., Bağrıaçık Ü., Akmansu M. Postmastektomi radyoterapi uygulanan meme kanserli olgularda gelişen yorgunluğun derecesi, serum sitokin ve leptin düzeyleri ile ilişkisi: Prospektif değerlendirme, Türk Onkoloji Dergisi. 2007;22(1):1-12.
Wong S., Kaur A., Back M., Lee KM., Baggarley S., Jay Lu J. An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy. Radiation Oncology. 2011; 6(9):1-10.
Wong RKS., Bensadoun RJ., Boers-Doets CB., Bryce J., Chan A., Epstein JB. et al. Clinical practice guidelines for the prevention and treatment of acute and late radiation reactions from the MASCC skin toxicity study group. Support Care Cancer. 2013; 21:2933–2948.
Yee C., Wang K., Asthana R., Drost L., Lam H., Lee J. et al. Radiation-induced skin toxicity in breast cancer patients: A systematic review of randomized trials. Clinical Breast Cancer. 2018; 18(5): e825-e840.
Yeter K, Savcı A, Sayıner FD. Meme kanserinde rekonstrüktif cerrahinin ve hasta eğitiminin yaşam kalitesine etkisi. Meme Sağlığı Dergisi 2009; 5(2): 65-68.
Yılmaz E., Coşkun T. Meme kanserli hastalarda üst ekstremite sorunları ve yaşam kalitesi. Bakırköy Tıp Dergisi. 2019; 15:29-37
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