THE FREQUENCY OF ROTAVIRUS AND ADENOVIRUS IN CASE OF GASTROENTERIT OBSERVED IN SİİRT REGION


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Authors

DOI:

https://doi.org/10.5281/zenodo.6974027%20

Keywords:

Adenovirus, acute gastroenteritis, rotavirus

Abstract

This study was aimed to retrospectively examine the frequency of Rotavirus and Adenovirus in patients with acute gastroenteritis admitted to our hospital, according to gender, age, and seasons over four years. The results of stool samples were sent to Siirt Training and Research Hospital Medical Microbiology Laboratory between January 1, 2017, and December 31, 2020, with the diagnosis of acute gastroenteritis and analyzed with Rotavirus and Adenovirus antigen tests were evaluated retrospectively. When the stool samples of 16689 patients were examined, it was determined that 2262 (13.6%) of the viral agents detected in 3077 (18.4%) of the patients belonged to Rotavirus and 815 (4.9%) of them belonged to Adenovirus. Adenovirus Rotavirus association was observed in 87 (0.52%) patients. When Adenovirus and Rotavirus positivity rates were examined, it was seen that there was no difference according to gender. Rotavirus was detected most frequently in autumn and Adenovirus in summer, and the difference was statistically significant. In our study, when the distribution of viral antigen positivity rates by age groups was examined; The highest positivity rate was found between 19.6% and 13-24 months for Rotavirus, and between 5.5% and 3-5 years for Adenovirus. Most children have Rotavirus and Adenovirus gastroenteritis by the age of 5 years. In our study, 2030 (89.7%) of 2262 patients with Rotavirus positive and 683 (83.8%) of 815 positive patients for Adenovirus were found under 5 years of age. In our study, it was also observed that Rotavirus and Adenovirus infections were less in 2020 compared to other years. Covid-19 pandemic conditions may have caused this situation. Quickly detecting the presence of viral agents in infectious gastroenteritis can prevent the use of unnecessary antibiotics as well as early initiation of the right treatment.

References

Akan, H., Izbırak, G., Gürol, Y., Sarıkaya, S., Gündüz, T.S., Yılmaz, G.,…Vitrinel, A. 2009. Rotavirus and adenovirus frequency among patients with acute gastroenteritis and their relationship to clinical parameters: a retrospective study in Turkey. Asia Pacific Family Medicine, 8:8.

Altındiş, M., Beştepe, G., Çeri, A., Yavru, S., Kalaycı, R. 2008. Akut ishal yakınmalı çocuklarda rotavirüs ve enterik adenovirus sıklığı. Süleyman Demirel Üniversitesi Tıp Fak Derg, 15: 17-20.

Aytaç, Ö., Şenol, F.F., Öner, P., Erkmen, N., Aslan, R., Doğukan, M., Aşçı, Toraman, Z. 2020. Akut gastroenteritli hastalarda Rotavirus ve Adenovirus sıklığı. Turk Hij Den Biyol Derg, 77(2): 179-184.

Borsa, B.A., Bahar Tokman, H., Çağatay, P. 2013. Mardin Kadın Doğum ve Çocuk Hastalıkları Hastanesi’nde 0-5 yaş arası akut gastroenteritli çocuklarda rotavirüs ve adenovirus sıklığının belirlenmesi. Ankem Derg, 27(2):75-9.

Bulut, Y., İşeri, L., Ağel, E., Durmaz, B. 2003. Akut Gastroenterit Ön Tanılı Çocuklarda Rotavirüs Pozitifliği. İnönü Üniversitesi Tıp Fakültesi Dergisi 10(3) 143-145.

Dinç, H.Ö., Taner, Z., Özbey, D., Gareayaghi, N., Sirekbasan, S., Kocazeybek, B.S. 2019. The Prevalence of Rotavirus and Adenovirus Childhood Gastroenteritis: data of the University Hospital of Cerrahpaşa Medical Faculty Between January 2013 and December 2018. January. Türk Mikrobiyoloji Cemiyeti Dergisi.

Farkas, T., Jiang XI. 2007. Rotaviruses, Caliciviruses, Astroviruses, Enteric Adenoviruses and other diarrheic viruses. In: Murray, P.R., Baron, E.J., Jorgensen, J.H., Landry, M.L., Pfaller, M.A. ed. Manual of clinical microbiology. 9th ed. Washington DC: ASM Press, 1453-69.

Ford, Jones, E.L., Wang, E., Petric, M., Corey, P., Moineddin, R., Fearon, M. 2000. Hospitalization for community-acquired, rotavirus-associated diarrhea: a prospective, longitudinal, population-based study during the seasonal outbreak. The Greater Toronto Area/Peel Region PRESI Study Group. Pediatric Rotavirus Epidemiology Study for Immunization. Arch Pediatr Adolesc Med, Jun;154(6):578-85.

Göktaş, Ş., Aksoy Gökmen, A., Şamlıoğlu, P., 2018. Akut Gastroenterit Etkenlerinin Moleküler Yöntemlerle Saptanması. Journal of Clinical and Experimental İnvestigations, 9:1.

Hamkar, R., Yahyapour, Y., Noroozi, M., Nourijelyani, K., Jalilvand, S., Adibi, L., Savad, Koohi, R. 2010. Prevalence of Rotavirus, Adenovirus,andAstrovirus Infections among Patients with Acute Gastroenteritis in, NorthernIran. Iran J Public Health, 39(2):45-51.

Midthun, K., Greenberg, H.B., Hoshino, Y., Kapikian, A.Z., Wyatt, R.G., Chanock, R.M. 1985. Reassortant rotaviruses as potential live rotavirus vaccine candidates. J Virol, 53(3):949–54.

Motamedifar, M., Amini, E., Shirazi, P.T. 2013. Frequency of rotavirus and adenovirus gastroenteritis among children in shiraz, iran. Iran Red Crescent Med. J. Aug;15(8): 729-33.

Ozdemir, S., Delialioğlu, N., Emekdaş, G. 2010. Investigation of Rotavirus, Adenovirus and Astrovirus frequencies in children with acute gastroenteritis and evaluation of epidemiological features, Mikrobiyol Bul, 44(4): 571-8.

Ozsari, T., Bora, G., Kaya, B., Yakut, K. 2016. The Prevalence of Rotavirus and Adenovirus in the Childhood Gastroenteritis. Jundishapur J Microbiol. June; 9(6): e34867.

Román, E., Wilhelmi, I., Colomina, J., Villar, J., Cilleruelo, M.L., Nebreda, V., Sanchez, Fauquier, A. 2003. Acute viral gastroenteritis: proportion and clinical relevance of multiple infections in Spanish children. J Med Microbiol, 52: 435-40.

Tanrıverdi, Çaycı, Y., Yılmaz, G., Birinci, A. 2017. Akut gastroenterit vakalarında rotavirüs ve adenovirus sıklığının araştırılması. Pam Tıp Derg, 10(1):61-5.

Topçu, AW., Söyletir, G., Doğanay, M. 2008. İstanbul Nobel Tıp Kitabevleri; Editör Ustaçelebi Ş. Enfeksiyon Hastalıkları ve Klinik Mikrobiyolojisi. Cilt 1. Sistemlere Göre Enfeksiyonlar. 3 Vol. 1. baskı, Adenovirusler [Adenoviruses] pp. 1696–98.

Wilhelmi, I., Roman, E., Sanchez Fauquier, A. 2003. Viruses causing gastroenteritis. Clinical Microbiology and Infection, Rewiew, Volume 9, Issue 4, P 247-262, 1 April.

World Health O. 2007. Rotavirus vaccines. Wkly Epidemiol Rec, 82(32):285–95.

Varışlı, A.N., Tekin, S., Bıçak, İ. 2019. Akut Gastroenterit Olgularında Rotavirus ve Adenovirus Ne Kadar Sorun?: Dört Yıllık Sonuçlar. Klimik Dergisi 2019; 32(1): 67-70.

Zaraket, R., Salami, A., Bahmad, M., El Roz, A., Khalaf, B. Ghssein, G., Bahmad, H.F. 2020. Prevalence, risk factors, and clinical characteristics of rotavirus and adenovirus among Lebanese hospitalized children with acute gastroenteritis. Heliyon. Jun; 6(6): e04248.

Published

2022-08-11

How to Cite

GENC BAHCE, Y., OZUDOGRU, O., & ACER, Ömer. (2022). THE FREQUENCY OF ROTAVIRUS AND ADENOVIRUS IN CASE OF GASTROENTERIT OBSERVED IN SİİRT REGION. GEVHER NESIBE JOURNAL OF MEDICAL AND HEALTH SCIENCES, 7(19), 23–28. https://doi.org/10.5281/zenodo.6974027

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