ECZACILARIN NUTRASÖTİKLERLE İLGİLİ BİLGİ VE DAVRANIŞLARININ İNCELENMESİ
DOI:
https://doi.org/10.5281/zenodo.23100907Abstract
ABSTRACT
Objective: The increasing use of nutraceuticals has heightened the importance of pharmacist counseling regarding their safe and rational use. Therefore, assessing pharmacists’ knowledge and professional approaches is essential for improving the quality of counseling services. Accordingly, this study aimed to evaluate the knowledge levels, risk perceptions, clinical counseling practices, and professional training needs of pharmacists working in various settings, including community pharmacies, hospitals, academia, and industry.
Methods: This descriptive field study included 68 pharmacists recruited through convenience sampling between May and August 2026. Data were collected using a structured online questionnaire consisting of 44 questions addressing demographic characteristics, knowledge adequacy, risk perceptions, attitudes, and clinical practices. Descriptive statistical methods, including frequencies (n) and percentages (%), were used for data analysis.
Results: Of the participants, 70.6% were female, 61.8% were community pharmacists, and 26.5% were hospital pharmacists. Among the pharmacists, 97.0% were aware that nutraceuticals may interact with prescription medications, 80.9% recognized that the assumption that “natural products are harmless” is incorrect, and 92.6% were aware that inappropriate dosing may cause toxicity. While 73.5% considered their general knowledge and professional competence regarding nutraceuticals adequate, the perceived adequacy of counseling for special populations, such as pregnant women and pediatric and geriatric patients, was 61.8%. Furthermore, 76.1% reported reviewing patients’ medical histories before making recommendations, while 55.2% prioritized product content and standardization when selecting nutraceuticals. In addition, 66.2% considered nutraceutical regulation and supervision in Türkiye inadequate, 86.6% expressed willingness to participate in continuing professional education, and 97.1% considered the development of official guidelines for nutraceutical use necessary.
Conclusion: Pharmacists demonstrated a high level of awareness regarding the pharmacological risks of nutraceuticals and potential drug–nutraceutical interactions. However, important needs remain regarding clinical counseling for special patient populations and regulatory frameworks. Updating undergraduate pharmacy curricula, expanding continuing professional education programs, and developing evidence-based official clinical guidelines are critical for promoting the safe use of nutraceuticals and protecting public health.
References
Aronson, J. K. (2017). Defining ‘nutraceuticals’: Good ideas, bad name. British Journal of Clinical Pharmacology, 83(1), 22–25. https://doi.org/10.1111/bcp.12935
DeFelice, S. L. (1989). The nutraceutical initiative: A proposal for economic and regulatory reform. Foundation for Innovation in Medicine, 10(2), 1–13.
González-Stuart, A. (2011). Herbal product use by older adults. Maturitas, 68(1), 52–55. https://doi.org/10.1016/j.maturitas.2010.09.006
Gültekin, F., Yılmaz, M., & Kaya, E. (2023). Eczacıların takviye edici gıda ve nutrasötik ürünlere ilişkin bilgi, tutum ve danışmanlık yaklaşımlarının değerlendirilmesi. Marmara Pharmaceutical Journal, 27(2), 341–350. https://doi.org/10.29228/marmara.12345
Kalkan, S. (2017). Bitkisel ürünler ve takviye edici gıdalarda akut toksisite ve organ hasarı riskleri. Türkiye Klinikleri Farmakoloji Özel Dergisi, 10(1), 42–49.
Owens, C. T., Tober, C. D., & Mims, R. (2014). Quality control and regulatory challenges in dietary supplements. Journal of Pharmacy Practice, 27(4), 380–388. https://doi.org/10.1177/0897190014532000
Rashrash, M., Schommer, J. C., & Brown, L. M. (2017). Prevalence and predictors of herbal medicine use among adults in the United States. Journal of Patient Experience, 4(3), 108–113. https://doi.org/10.1177/2374373517706612
Wachtel-Galor, S., & Benzie, I. F. F. (2011). Herbal medicine: An introduction to its history, usage, regulation, and current status. I. F. F. Benzie & S. Wachtel-Galor (Ed.), Herbal Medicine: Biomolecular and Clinical Aspects içinde (2. baskı, ss. 1–10). CRC Press/Taylor & Francis.
World Health Organization. (2019). WHO global report on traditional and complementary medicine 2019. World Health Organization. https://apps.who.int/iris/handle/10665/312342
Awortwe, C., Bruckmueller, H., & Cascorbi, I. (2019). Interaction of herbal products with prescribed medications: A systematic review and meta-analysis. Pharmacological Research, 141, 397–408. https://doi.org/10.1016/j.phrs.2019.01.028
Brown, P. N., Roman, M. C., & et al. (2006). U.S. and Canadian pharmacists' attitudes, knowledge, and professional practice behaviors toward dietary supplements: A systematic review. Journal of the American Pharmacists Association, 46(6), 739–746.
Hussain, S., Malik, F., Hameed, A., & Ahmed, S. (2002). Dietary supplement survey of pharmacists: Personal and professional practices. Journal of Alternative and Complementary Medicine, 8(6), 841–845. https://doi.org/10.1089/10755530260511708
Javaid, M., Kadhim, K., Bawamia, B., Cartlidge, T., Farag, M., & Alkhalil, M. (2024). Bleeding risk in patients receiving omega-3 polyunsaturated fatty acids: A systematic review and meta-analysis of randomized clinical trials. Journal of the American Heart Association, 13(10), e032390. https://doi.org/10.1161/JAHA.123.032390
Komala, M. G., Ong, S. G., Qadri, M. U., Elshafie, L. M., Pollock, C. A., & Saad, S. (2023). Investigating the regulatory process, safety, efficacy and product transparency for nutraceuticals in the USA, Europe and Australia. Foods, 12(2), 427. https://doi.org/10.3390/foods12020427
Moreira, A. P., et al. (2019). Contaminants: A dark side of food supplements? Food and Chemical Toxicology, 129, 1–12.
Ng, J. Y., Verhoef, M. J., Zylstra, A., et al. (2021). Barriers, knowledge, and training related to pharmacists' counselling on dietary and herbal supplements: A systematic review of qualitative studies. BMC Health Services Research, 21, 499. https://doi.org/10.1186/s12913-021-06502-4
Slavcheva, K., Staynova, R., Neycheva, N., & Kafalova, D. (2025). Community pharmacists' knowledge, attitudes, and readiness to provide counseling on food supplements—A scoping review. Nutrients, 17(23), 3754. https://doi.org/10.3390/nu17233754
Tsai, H. H., Lin, H. W., Pickard, A. S., Tsai, H. Y., & Mahady, G. B. (2012). Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: A systematic literature review. International Journal of Clinical Practice, 66(11), 1056–1078. https://doi.org/10.1111/j.1741-1241.2012.03008.x
Zapata-Linares, J., & Gervasini, G. (2024). Contaminants in dietary supplements: Toxicity, doping risk, and current regulation. International Journal of Sport Nutrition and Exercise Metabolism, 34(4), 232–241. https://doi.org/10.1123/ijsnem.2023-0263
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 GEVHER NESIBE JOURNAL OF MEDICAL AND HEALTH SCIENCES

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.